Induction of Cellular Dna Synthesis by Polyoma Virus.
نویسندگان
چکیده
منابع مشابه
DNA synthesis in temperature-sensitive mutants of the cell cycle infected by polyoma virus and adenovirus.
tsAF8 cells are a temperature-sensitive (ts) mutant of BHK cells that are arrested in G1 at the nonpermissive temperature. When made quiescent by serum restriction, they can be stimulated to enter S phase by 10% serum at 34 degrees C but not at 40.6 degrees C. The same results can be obtained if quiescent cells are infected with polyoma virus or adenovirus 12 instead of serum. However, adenovir...
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Normal and transformed BHK-21 cells are heterogeneous in their capacity to support replication of polyoma virus. In situ hybridization has been used to demonstrate rare cells in which large numbers of polyoma genomes accumulate following infection by wild-type virus or induction of polyoma A gene mutants. Different transformed cell lines vary in the frequency of occurrence of these rare cells. ...
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 53 6 شماره
صفحات -
تاریخ انتشار 1965